We protect
the genome.
DNA damage is the cause of cancer and a major driver of aging
Mutations drive cells toward dividing rapidly and uncontrollably, leading to oncogenesis
As we age, DNA damage leads to genome instability, epigenetic entropy, and a loss of cellular identity
Cellular dysregulation causes systemic inflammation, accelerating disease progression
Permanence Bio is developing therapeutics that act at the root of disease
Preventing DNA damage would lead to the prevention of cancer, treatments for patients with acute ophthalmological and renal illnesses, and cures for patients with numerous genetic diseases
Protecting the genome can save the lives of those exposed to radiation and chemical hazards
Our approach incorporates a high-throughput screening platform that drives artificial intelligence for the discovery of genome-stabilizing therapies
Our team is deeply passionate about the mission
We aspire to make a meaningful change in the world by changing how we think about disease: prioritizing the prevention of core drivers of illness
We are advised by many of the world’s experts in cancer prevention, medicinal chemistry, and longevity
